Genetics and Genomics for the Practicing Clinician: A Case-Based Approach

June 1 from 7:30 AM-11:00 AM
McCormick Place, Room S103​

Course Description

This course will focus on cancer genomics and cancer genetics specifically for the clinician in a half-day format using real-world case-based discussion with renowned experts. It will cover both tumor and inherited genetic variation, as well as explain the variety of tests available to the clinician and when they should be administered. Implications on management and screening will also be discussed. Audience response questions will be incorporated into case presentations and the session will conclude with audience Q&A and discussion with a diverse panel of experts. With the proliferation of academic and commercial genetic tests, and the increasing utilization of matched tumor/normal sequencing with the potential for incidental findings, these topics are particularly relevant for clinicians in academic and community practices.

Go to to view session slides on your personal device in real time, take notes on slides, pose questions to faculty, and participate in audience polling. Link will be live when the session begins on Friday, June 1.

Course Agenda

Note: Session faculty will be added to the agenda below as presenters are confirmed.

7:00 AM - 7:30 AM Breakfast
7:30 AM - 10:00 AM

Case Presentations

Marie Wood, MD—Chair
University of Vermont


James M. Ford, MD
Stanford University School of Medicine
Case #1: Curation and Reclassification of Germline Variants


Marie Wood, MD
University of Vermont
Case #2: Incidental Germline Findings from Tumor Genomic Testing


Zsofia K. Stadler, MD
Memorial Sloan Kettering Cancer Center
Case #3: Somatic MSI and Implications for Germline Testing and Treatment


Philippe L. Bedard, MD, FRCPC
Princess Margaret Cancer Centre
Case #4: Detection and Management of Clonal Hematopoiesis (CHIP)


Case Presenter Discussion

10:00 AM - 10:15 AM Break
10:15 AM - 11:00 AM

Panel Discussion

Michael F. Berger—Chair
Memorial Sloan Kettering Cancer Center


Y. Nancy You, MD
University of Texas MD Anderson Cancer Center
Clinician Perspective


David Liu, MD, MPH
Dana-Farber Cancer Institute
Bioinformatics Scientist Perspective


Heather Hampel, MS, LGC
The Ohio State University Comprehensive Cancer Center
Genetic Counselor Perspective


Laura Beamer, PhD, DNP, AOCNP, AOC
Norther Illinois University
Nurse Practitioner Perspective


Jeremy Segal, MD, PhD
The University of Chicago
Pathologist Perspective

Course Committee

View Course Committee Disclosures

Michael F. Berger, PhD (Co-Chair)
Memorial Sloan Kettering Cancer Center

Marie Wood, MD, MPH​ (Co-Chair)​
University of Vermont

Banu Arun, MD, MPH
University of Texas MD Anderson Cancer Center

Philippe Bedard, MD, FRCPC
Princess Margaret Cancer Centre

Kathleen Calzone, PhD, RN, APGN, FAAN
National Cancer Institute

Elaine Mardis, PhD
Nationwide Children's Hospital

Therese Mulvey, MD, MPH
Southcoast Hospitals Group

Christian Thomas, MD
New England Cancer Specialists


 "Jointly Accredited Provider, Interprofessional Continuing Education"

In support of improving patient care, the American Society of Clinical Oncology is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

AMA Credit Designation Statement - Physicians

The American Society of Clinical Oncology Designates this live activity for a maximum of 2.75 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ANCC Credit Designation Statement - Nurses

The maximum number of hours awarded for this CE activity is 2.75 contact hours. 

AAPA/NCCPA Credit Designation Statement - Physician Assistants

Physician Assistants may claim a maximum of 2.75 Category 1 credits for completing this activity. NCCPA accepts AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. 

All non-physician attendees are welcome to submit a request for a Certificate of Participation, which may enable non-physicians to apply their meeting participation toward re-licensure. Please note, however, that all final decisions regarding certificate acceptance will be made by the licensing organization to which the certificate is submitted. 

Target Audience

The 2018 Genetics and Genomics for the Practicing Clinician: A Case-Based Approach course is designed for the cancer care team; credit is offered for physicians and nurses, but all are encouraged to participate, as they may be able to apply for credit through their own licensing organization.

Learning Objectives 

Upon participation in this activity, attendees will be able to:

  • Using cases, discuss methods of germline genetic testing and implications of findings
  • Discuss the appropriate management of incidental germline findings from tumor genomic testing
  • Review somatic microsatellite instability and significance for germline testing and treatment
  • Evaluate genetic and genomic testing from an interdisciplinary perspective

Disclaimer/Unlabeled Usage Statement         

The information presented is that of the contributing authors and does not necessarily represent the views of the American Society of Clinical Oncology and/or any named commercial entity providing financial support. Specific therapies discussed may not be approved and/or specified for use as indicated. Therefore, before prescribing any medication, please review the complete prescribing information including indications, contraindications, warnings, precautions and adverse effects.